Exposure to ambient air pollution is a major risk factor for human health yet, the physiological effects of particulate matter (PM) remain poorly understood. Oxidative stress due to excess formation of reactive oxygen species (ROS) is a leading hypothesis for the molecular mechanism behind the adverse health effects of PM. Thus, measurements of ROS production… Continue reading Aerosol oxidative potential and reactive species predicted with a chemical kinetics model (KM-OP)
Author: Vanessa Köhler
The dark night as a cardiovascular vital sign: personal light exposure, subclinical cardiac remodelling, and the urban exposome
Artificial light at night is an increasingly widespread environmental exposure, but its potential effects on cardiovascular health are only beginning to be understood. In this editorial, MARKOPOLO researchers discuss new findings from a large UK Biobank study investigating the relationship between nighttime light exposure and heart health. The study included more than 11,000 participants with… Continue reading The dark night as a cardiovascular vital sign: personal light exposure, subclinical cardiac remodelling, and the urban exposome
Non-optimal temperatures and health impact with focus on cardiovascular diseases
Dr. Omar Hahad, Postdoctoral Research Fellow and Epidemiologist at University Medical Center Mainz, explores how heat and cold affect cardiovascular health, and why cold currently accounts for more temperature-related deaths than heat.
Kinetic computational model for lung damage by particulate matter
Dr. Thomas Berkemeier, group leader at Max Planck Institute for Chemistry explains how computational models reveal the chemistry linking air pollution to oxidative stress and disease, and why some pollutants are more harmful than others.
Noise pollution health impact and redox considerations
Prof. Thomas Münzel, Senior professor at University Medical Center Mainz, shows the mechanisms linking noise, oxidative stress, inflammation, and vascular dysfunction, and why nighttime noise is particularly harmful.
Mini Masterclass Series
We are pleased to launch the MARKOPOLO Mini Masterclass Series. Starting from today, each week, we’ll post a new lecture, given by our esteemed MARKOPOLO consortium members during the EXPOHEALTH Premeeting Symposium in Mainz in June 2026. All MARKOPOLO masterclasses and our training content can be found on our website: https://markersofpollution-markopolo.eu/training/masterclasses/
The exposome concept
Prof. Andreas Daiber, Head of the Laboratory of Molecular Cardiology at University Medical Center Mainz and scientific coordinator of MARKOPOLO EU Project, introduces the exposome concept, a framework for understanding how environmental and lifestyle factors shape human health throughout life.
Changes of Long‐Term Exposure to Ultrafine Particles From 2010 to 2019 in High Income Countries in Relation to Cardiovascular Diseases
What is already known? What does this study add? What is the clinical significance?
Nano- and microplastics in the cardiovascular exposome: a new frontier in environmental risk
Cold Exposure, Sunlight, and Particulate Matter in Acute Heart Failure: Signals and Uncertainties
Note: Accepted for publication by the journal but prior to copyediting or typesetting. Might be subject to changes.
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