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Recent updates

12
DEC

29th ETH Nanoparticle Conference 2026

The Nanoparticles Conference functions as an interdisciplinary forum focusing on all aspects of nanoparticles...
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11
DEC

ICBEN Conference 2026

ICBEN conference from 14 - 18 June 2026 organized by MARKOPOLO member Mette Sørensen
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09
DEC

Save the Date: SFFR-E Annual Meeting in June 2026 in Mainz

The 2026 Society for Free Radical Research Europe (SFRR-E) conference hosted by SFRR-E will be held from June...
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04
DEC

Bridging Science: Setting up a Noise Exposure System in the US

Doctoral student Arijan Valar is currently working at the Del Monte lab to establish a complex noise exposure system for animal studies.
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24
NOV

MARKOPOLO in action – air pollution data from the streets of Denmark

A specially equipped car is currently collecting high-resolution data on air pollution ...
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14
NOV

New key publication on global UFP concentrations

The study Global high-resolution ultrafine particle number concentrations through data fusion with machine learning by...
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13
NOV

13 Nov 2025: HYGIEIA webinar

On Thursday, 13 November 2025, our coordinator Andreas Daiber will be speaking at the webinar of the Joint...
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01
OCT

ExpoHealthNet Cluster Meeting 2025

Last week, our MARKOPOLO team had the pleasure of joining the very first ExpoHealthNet Cluster Meeting in Barcelona!...
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15
JUL

First Newsletter out – Insights Summer 2025

The first MARKOPOLO Insights newsletter is out!Discover how our EU-funded project is advancing research in the field of...
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About MARKOPOLO

Traffic noise and air pollution, especially particulate matter (PM) and ultrafine particles (UFP), are closely linked environmental risk factors that contribute significantly to the development of diseases such as diabetes, hypertension and atherosclerosis.

MARKOPOLO aims to investigate the impact of traffic noise and air pollution, especially fine and ultrafine particulate matter, on human health through an innovative translational approach. Experimental and computational models are used in clinical, interventional and epidemiological studies.

One of the main objectives is to identify disease-relevant biomarkers and to understand the molecular mechanisms involved in diseases of the brain, lung and cardiovascular system. The “from bench-to-bedside” approach uses extensive knowledge of the brain-heart connection and applies modern methods to better understand the causes of disease.

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Our vision & objectives

MARKOPOLO will advance our understanding of the complex interplay between noise, air pollution, and human well-being.

We aim to close gaps in knowledge and strengthen the evidence base for pollution-disease associations for traffic noise and air pollution (PM including UFP), especially synergetic interactions, and accounting for effects in susceptible groups and in different genders.
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We take a unique translational approach by implementing experimental/computational models, and clinical and epidemiological studies to provide FAIR data on associations between exposures and health outcomes.
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A primary goal is to identify disease-relevant biomarkers and causality mechanisms to understand the biological pathways of cerebral, pulmonary and cardiovascular health outcomes.
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Our “bench to life” approach is entirely driven by profound preclinical mechanistic knowledge and will use novel multiomics methodology (e.g. redox/phospho-proteomics and “spatial” epigenetics), allowing the analysis of key pathomechanisms, to be included in exposure-response models. This will improve risk assessment and allow evaluation of the effectiveness of mitigation strategies.
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We will also consider the societal circumstances and policies at the national level and their impact on different stakeholders.
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